objective: in spite of introduction of novel drugs, obsessive-compulsive disorder (ocd) has still found no suitable treatment. on the other hand, high rates of co-morbidity of ocd with bipolar spectrum disorders are increasingly recognized. mood switching and development of rapid cycling with antidepressants are significant problems in these patients. from this viewpoint, introducing a non-anti...

objective: although there are some reports of reduction of obsessive-compulsive symptoms in manic episodes or its exacerbation during depressive episodes, this relationship has not been proved. method: clinical observations of six cases with co-morbidity of bipolar-i-disorder and obsessive-compulsive disorder or symptoms. results: the cases presented here show heterogeneity and variety of the r...

ôbjective: the mood disorder questionnaire (mdq) has been developed as a self-reporting, brief, and easy-to-use screening instrument to improve identification of bipolar mood disorders. the goals of the present study were to examine the prevalence of this disorder and interrelationship of its symptoms by factor analysis of mdq in a group of pregnant women in ïran. methods: ône thousand and eigh...

objective: vitiligo is a rare side effect of carbamazepine whose exact mechanism is unknown. the aim of this report is to describe a single case of vitiligo induced by carbamazepine . methods: the case was a patient with bipolar i disorder whose medications were changed from valproate to carbamazepine and who developed vitiligo after a short while. we followed the case for about four years when...

bipolar spectrum disorders may often go undiagnosed or unrecognized. the aim of this study was to determine the proportion of bipolar disorder symptoms in iranian patients with a major depressive episode.313 patients with a current dsm-iv-tr (diagnostic and statistical manual of mental disorders 4th ed. text rev.) diagnosed with a major depressive episode entered this cross-sectional study. thi...

conclusions the obtained results confirm some previous studies regardinga gender specific association of maoa gene with the bipolar disorder. results significant associations were observed regarding maoa-ca (p = 0.016) and maoa-vntr (p = 0.004) polymorphisms in the bipolar females. there was no association between maoa-rflp and bipolar disorder. patients and methods this study is a case-control...

introduction : the aim of this study was to compare obsessive-compulsive disorder (ocd) comorbidity in early and late onset bipolar i disorder and to explore the pattern of obsessive symptoms in these two groups. methods : a total of 100 inpatients with early and late bipolar disorder were admitted in the child, adolescent and adult psychiatric ward. they were recruited to the study through con...

introduction: substance abuse/dependency is one of the most important comorbidity in bipolar patients. therefore, recognizing the patterns of substance use is valuable in treatment and management of patients. this study was conducted to determine patterns of substance abuse among bipolar patients who were hospitalized in an educational hospital. methods : this was a descriptive-analytical study...

background lithium is a drug for treatment of bipolar disorder by correcting mania and reducing depressive mood swings. objectives in this study, effects of lithium on volumetric parameters of cerebellum were investigated using stereological methods. materials and methods in this experimental study, 20 sexually mature wistar male rats were selected and divided in two groups randomly (n = 10). a...

objective: bipolar disorder is a severe mental disorder, and its prevalence is around 1% to 2%. despite a vast literature around bipolar disorder, the reasons of its nonadherence and rehospitalization is still obscure. several symptoms of bipolar disorder include changes in activity level, cognitive abilities, speech, and vegetative functions, such as sleep, sexual activity, as well as aggressi...